Pharmaceutical Powders Test Sieve

What is a pharmaceutical powders test sieve?

Pharmaceutical powders test sieve is a standardized laboratory device used to analyze the grading and distribution of pharmaceutical powders particles. It separates powders particles through sieves of different apertures (1µm-500µm) to determine the uniformity, quality and distribution of particle size, meeting the pharmaceutical industry's requirements for drug solubility, stability and production consistency. The test sieve supports dry sieving, wet sieving or screening, with high precision (99% screening rate), non-standard customization (such as 1µm sieve), and is equipped with ultrafine powders (5-20µm), fine powders 2-100µm) and medium powders (100-500 µm) testing needs.

Vodeo of pharmaceutical powders test sieve

What types of pharmaceutical powders test sieves are there?

Classification by screen material:

Screen material	picture	features	scope of application
Stainless steel screen		corrosion-resistant, wear-resistant, easy to clean, widely used	various pharmaceutical powders
Nylon screen		wear-resistant, good elasticity, suitable for some special powders	partial pharmaceutical powders
Wire mesh screen		high precision, suitable for fine screening	ultrafine powders

Classification by type:

Depending on the screening method, pharmaceutical powders test sieves can be divided into manual sieves, vibrating sieves, ultrasonic sieves and other types. Manual sieves are suitable for screening small batches of samples; vibrating sieves improve screening efficiency through vibration; ultrasonic sieves use the vibration energy of ultrasonic waves to more effectively separate powders that are difficult to screen.

Classification by the number of screen layers:

Number of screen layers	picture	features	scope of application
Single-layer screen		Only one screen, used to separate powders of specific particle size	Simple particle size separation
Multi-layer screen		Multiple screens with different apertures are superimposed to complete the screening of multiple particle sizes at one time	Complex particle size analysis

Classification by screening environment:

Dry test sieves are screened in a dry environment and are suitable for screening of most powders and conventional pharmaceutical powders. Wet test sieves are screened in liquid media and are suitable for easily agglomerated or extremely fine powders, easily agglomerated powders (such as nanometers) or screening that requires the assistance of liquid media.

Classification by particle size of pharmaceutical powders

Pharmaceutical powders test sieves are divided into 12 grades according to the particle size range, and the registered sieve sizes are 1µm, 5µm, 10µm, 20µm, 38µm, 75µm, 106µm, 150µm, 250µm, 355µm, 500µm and 1000µm. These grades cover:

Ultrafine powders (1-20 µm): 1-3 grades, using nylon/SS316 sieves combined with airflow/ultrasonic sieving for inhaled drugs.

Fine powders (20–100 µm): 4-6 grades, using SS316/nylon sieves as tablet excipients.

Medium powders (100–500 µm): 7–9 grades, using SS316/alloy sieves to obtain particles.

Coarse powders (500–1000 µm): 10–12 grades, use SS316/alloy/brass sieves to obtain specialty particles.

How does the pharmaceutical powders test sieve work?

The working principle of the pharmaceutical powders test sieve is based on the basic concept of particle physics. Through a series of sieves with different apertures, pharmaceutical powders can be separated layer by layer according to the difference in particle size under the influence of external factors such as gravity and vibration. The fine pharmaceutical powders particles can easily pass through the sieve, while the larger pharmaceutical powders particles are blocked above, forming a clear layered structure.

Functions of pharmaceutical powders test sieve

Pharmaceutical powders test sieves are key tools in the pharmaceutical industry for analyzing and controlling the particle size distribution of pharmaceutical powders (1-1000µm, prone to static electricity, hygroscopicity) used in pharmaceutical formulations (e.g. tablets, capsules, inhalers, injections). Their function ensures the quality and consistency of powders.

Particle classification: In the pharmaceutical process, raw materials or intermediate products need to be classified to ensure that particles of different particle sizes are used in different preparation processes or as raw materials for different products. Pharmaceutical powders test sieve can classify powders according to the predetermined particle size range to improve product quality.

Foreign matter screening: During the production process of raw materials or finished drugs, foreign matter such as metal fragments, plastic particles, etc. may be mixed in. The use of pharmaceutical powders test sieves can effectively screen out these foreign matter and ensure the safety of drugs.

During the mixing process, the use of pharmaceutical powders test sieves can take samples to check the uniformity of drug mixing to ensure that no particle size segregation occurs.

Powders flowability evaluation: Pharmaceutical powders test sieve can also be used to evaluate the flowability of powders, which is very important for processes such as powders filling and capsule filling.

The structure of pharmaceutical powders test sieve

The structural design of the pharmaceutical powders test sieve focuses on precision, durability and cleanliness, and adapts to the unique characteristics of pharmaceutical powders (e.g. static charge, hygroscopicity, GMP requirements). The structure includes a sieve frame, a screen and a support assembly.

The structure of pharmaceutical powders test sieve includes the sieve frame, sieve mesh, cover, base, motor and vibration device and other accessories. These components work together to achieve accurate screening and quality control of pharmaceutical powders.

What are the advantages of pharmaceutical powders test sieve?

Pharmaceutical powders test sieve has significant advantages in ensuring powders quality, process efficiency and regulatory compliance, and can meet the challenges faced by pharmaceutical powders. Dahan Mechanical Test Sieve can be tailored to the screening situation and powders characteristics.

Solve the problem of pharmaceutical powders agglomeration: When screening pharmaceutical powders, vibration can effectively break the molecular forces between powders and disperse the agglomerates into single particles. The high-frequency micro-vibration of the pharmaceutical powders test sieve can break up the agglomerates and ensure that the powders participates in the screening in the form of single particles.

Deal with the problem of static electricity in pharmaceutical powders: Some pharmaceutical powders test sieves add antistatic materials during the screen making process, such as mixing fibers with antistatic properties into stainless steel woven mesh. Antistatic materials can neutralize the static electricity generated by pharmaceutical powders during the screening process and reduce the impact of static electricity on the powders.

Solve the problem of long screening time: Use a pharmaceutical powders test sieve, adjust the vibration frequency and amplitude, make the powders move fully on the screen, use a multi-layer screen, and perform screening of multiple particle sizes to improve work efficiency.

Solve the problem of pharmaceutical powders loss: Pharmaceutical powderS test sieve uses a closed screening device to reduce the escape of pharmaceutical powders. Equipped with a dust removal device to collect the escaped fine powders.

Core parameters of pharmaceutical powders test sieve

Parameter category	Parameter name	Typical range or options
Screen parameters	Aperture size	20μm-5mm
Screen parameters	Screen material	Stainless steel, nylon, special alloy
Screen parameters	Screen diameter	75 mm, 100 mm, 200 mm, 300 mm
Screening equipment parameters	Vibration mode	Mechanical vibration, ultrasonic vibration, airflow assistance
Screening equipment parameters	Vibration frequency	50Hz-60 Hz
Screening equipment parameters	Amplitude	0.5mm-3 mm
Screening equipment parameters	Screening time	1 minute-30 minutes
Sample parameters	Sample amount	10g-500g
Sample parameters	Powder characteristics	Particle size, humidity, viscosity
Environmental parameters	Temperature	20°C-25°C
Environmental parameters	Humidity	40%-60% RH
Standard parameters	Compliant standards	USP, EP, JP, ISO 3310-1
Other parameters	Screening method	Dry screening, wet screening
Other parameters	Collection method	Bottom collection, layered collection

Specifications of pharmaceutical powders test sieves

Sieve	sieve hole size	mesh specification	powder classification
No. 1 sieve	largest, usually 2mm	10 mesh	the coarsest powder can all pass through the No. 1 sieve, but mixed with powder that can pass through the No. 3 sieve and not more than 20%
No. 2 sieve	0.85mm	24 mesh	coarse powder can all pass through the No. 2 sieve, but mixed with powder that can pass through the No. 4 sieve and not more than 40%
No. 3 sieve	0.355mm	50 mesh
No. 4 sieve	0.25mm	65 mesh	medium powder can all pass through the No. 4 sieve, but mixed with powder that can pass through the No. 5 sieve and not more than 60% % of powder
No. 5 sieve	0.18mm	80 mesh	Fine powder can all pass through No. 5 sieve, and contains no less than 95% of powder that can pass through No. 6 sieve
No. 6 sieve	0.15mm	100 mesh	The finest powder can all pass through No. 6 sieve, and contains no less than 95% of powder that can pass through No. 7 sieve
No. 7 sieve	0.125mm	120 mesh
No. 8 sieve	0.09mm	150 mesh	Extra fine powder can all pass through No. 8 sieve, and contains no less than 95% of powder that can pass through No. 9 sieve
No. 9 sieve	The smallest, 0.075mm	200 mesh

Detailed solutions for pharmaceutical powders test sieves

The application scope of pharmaceutical powders test sieve in the pharmaceutical industry is very wide, covering multiple fields and links such as raw material production, preparation production, quality control and testing, new drug research and development and process optimization, as well as laboratory and scientific research. It is one of the indispensable and important tools in the pharmaceutical industry, providing a strong guarantee for the quality and safety of drugs.

Precautions for pharmaceutical powders test sieve

When using the pharmaceutical powders test sieve, it is necessary to ensure that the sieve and the receiving container are dry and clean to avoid affecting the screening results.

Pay attention to safety during the screening process to avoid personal injury or equipment damage caused by equipment failure or improper operation.

The analysis of the screening results needs to be judged and interpreted in combination with specific application scenarios and industry standards.

Pharmaceutical powders test sieve manufacturer

Dahan focuses on pharmaceutical powders test sieves, providing standard pharmacopoeia sieves, laboratory test sieves and customized solutions for pharmaceutical applications. The products are widely used in pharmaceutical powders (1-1000µm), such as particle size analysis, quality control and impurity removal of APIs, excipients and granules.

Why choose Dahan mechanical test sieve?

Pharmaceutical powders test sieve can accurately separate 2-7 particle segments at the same time, suitable for screening materials in different forms such as powders, liquids, and granules

The screening mesh range is wide (3.5 mesh-400 mesh), and with ultrasonic test sieve technology, fine powders classification can be achieved

Special models and models can be designed according to customer needs to meet personalized usage scenarios.

The company focuses on technological innovation and international exchanges, has a high-quality team, and can provide customers with professional technical consultation and support.

Provide one-stop services before, during and after sales, including equipment installation, commissioning, training and maintenance, to ensure that customers have no worries.